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Symbol
Name
ID
Cyfip2
cytoplasmic FMR1 interacting protein 2
MGI:1924134
Phenotype annotations related to nervous system
*Aspects of the system are reported to show a normal phenotype.
Darker colors indicate more annotations
Human Phenotypes
Microcephaly
Spasticity
Ventriculomegaly
Cerebral atrophy
Cerebellar atrophy
EEG with burst suppression
Hypsarrhythmia
Absent speech
Hyperreflexia
Epileptic encephalopathy
Seizure
Disease(s) Associated with CYFIP2
developmental and epileptic encephalopathy 65

Mouse Phenotypes
nervous system phenotype
abnormal hindbrain morphology
abnormal dendritic spine morphology
decreased miniature excitatory postsynaptic current frequency
increased prepulse inhibition
Availability Mouse Genotype
Cyfip2M1N/Cyfip2M1N
Cyfip2tm1a(EUCOMM)Wtsi/Cyfip2tm1a(EUCOMM)Wtsi
Cyfip2tm1(KOMP)Vlcg/Cyfip2+ *

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory